Colorado (1-6, 1-3) at No. 2 Oregon ( 7-0, 4-0 Pac-12), 3 p.m. ET (Pac-12 Network)
Line: Oregon by 45 ½.
Series Record: Tied 8-8.
WHAT'S AT STAKE
After the game at Autzen Stadium against the Buffaloes, the Ducks play three of their final four games on the road, including the big game on Nov. 3 against Pac-12 South leader USC in Los Angeles. Oregon has won 10 straight games, second only to Alabama with 11 straight victories. The Ducks have scored at least 42 points in those 10 games. Colorado has lost three straight and might be the worst team in a BCS automatic qualifying conference.
Oregon's high-scoring, speedy-spread offense against Colorado's defense. One look at the line should show where this game is headed. Oregon is ranked No. 8 in total offense, averaging 529.6 yards, while Colorado's overall defense is ranked 112th nationally, allowing an average of 489 yards. As for scoring, Oregon is averaging 51 points per game, while Colorado is allowing 42.6 points per game. The Buffaloes have allowed at least 50 points in back-to-back games.
PLAYERS TO WATCH
Colorado: QB Jordan Webb. The junior struggled last week when he threw three interceptions in a 50-6 loss to No. 11 USC, but coach Jon Embree says he's sticking with his starter for now. Webb has thrown for 1,351 yards, eight touchdowns and seven interceptions this season, and has a 5-23 record overall as a starter with CU and Kansas. Webb was replaced by backup Connor Wood against the Trojans.
Oregon: RB Kenjon Barner. The senior, who for the past two years has played in the shadow of LaMichael James, is increasingly getting Heisman buzz this season. Barner is averaging 124.3 yards rushing per game, 10th in the nation. He needs 130 yards rushing to become the 15th Oregon player in school history to rush for 1,000 yards in a season.
FACTS & FIGURES
Colorado is 2-5 all-time in the state of Oregon, with both wins coming in Eugene. ... Oregon has started 7-0 for the second time in three seasons. The Ducks were undefeated in 2010 before falling to Auburn in the BCS championship game. Last season the Ducks lost their opener to LSU. ... Colorado senior DE Will Pericak has started every game of his career, a string of 44 games dating back to the Buffs' opener in 2009. ... The Ducks lead the nation in red zone defense, allowing opponents just 15 scores in 29 trips, and only four touchdowns.