PARIS (AP) -- Jerzy Janowicz of Poland saved one match point on his way to a 5-7, 7-6 (4), 6-2 upset over third-seeded Andy Murray in the third round of the Paris Masters on Thursday.
Murray, the reigning Olympic and U.S. Open champion, served for the match at 5-4 in the second set, but completely lost his composure and the ensuing tiebreaker as the 69th-ranked Janowicz evened the match.
Murray's loss came one day after second-seeded Novak Djokovic exited with a second-round loss to big-serving American Sam Querrey.
With Roger Federer and Rafael Nadal not playing in the tournament, none of the so-called "Big Four" are left. Fifth-seeded Tomas Berdych reached the last eight earlier Wednesday, while fourth-seeded David Ferrer of Spain was scheduled to play later.
Janowicz had the momentum after controlling the tiebreaker and broke Murray twice in the deciding set as he raced to a 5-1 lead. Serving for the match, the 21-year-old saved three break points and secured the win on his second match point with a forehand winner. He then slumped to the ground and broke down in tears as he held his head in his hands.
Murray broke in the 11th game to get the chance to serve for the first set, but had so save a break point with a crosscourt forehand winner before clinching it when Janowicz's forehand bounced out.
Murray broke in the seventh game of the second set with a forehand return winner, and looked as though he was coasting to victory.
Serving for the match, Murray started to get flustered and his temper got the better of him as he smacked his hand against his forehead and then muttered to himself after Janowicz saved a match point. Two unforced backhand errors from Murray then helped Janowicz break for 5-5.
Janowicz clinched the tiebreaker when he returned Murray's weak second serve with an exquisite drop shot that Murray patted into the net.
Earlier, Berdych recovered from a poor first set to beat Kevin Anderson of South Africa 1-6, 6-3, 6-4.
The Czech was overpowered by Anderson's serve and strong defense in the first set, where Anderson hit six aces and broke Berdych twice, while saving all three break points he faced.
"The way that Kevin started was incredible. I had no chance, everything went on his side," Berdych said. "There were not many chances for me but I still had the hope and belief I could make it."
Berdych recovered and broke Anderson in the eighth game of the second set, and again in the seventh game of the decider before clinching the match with a backhand volley at the net.
He next plays Gilles Simon of France, who advanced without hitting a ball after 15th-seeded Kei Nishikori of Japan pulled out because of a recurrence of his right ankle injury.
With so many big names out of the way, Berdych is in a strong position to add to his 2005 title at the Bercy arena.
"It's a really new role to be (a favorite) in the tournament," Berdych said. "I can't forget my next opponent, playing the French at home is always tough."
Berdych had a heated argument with the chair umpire in the eighth game of the second set, when he thought he had broken Anderson, only for the point to be replayed.
Berdych shouted "What kind of call was that?" and threw his towel in the air as he walked off, prompting jeers from the crowd. After securing the break, however, he evened the match with an ace on set point and yelled "Yes!" as he clenched his fist.
Later Thursday, Ferrer was playing No. 16 Stanislas Wawrinka of Switzerland, and sixth-seeded Jo-Wilfried Tsonga of France was up against No. 11 Nicolas Almagro of Spain.