Kansas City Royals (22-48, fifth in the AL Central) vs. Minnesota Twins (47-22, first in the AL Central)

Milwaukee Brewers (39-31, second in the NL Central) vs. San Francisco Giants (30-38, fifth in the NL West)

Toronto Blue Jays (25-45, fourth in the AL East) vs. Houston Astros (48-23, first in the AL West)

Philadelphia Phillies (39-31, second in the NL East) vs. Atlanta Braves (41-30, first in the NL East)

Chicago Cubs (39-31, first in the NL Central) vs. Los Angeles Dodgers (47-24, first in the NL West)

San Diego Padres (34-37, fourth in the NL West) vs. Colorado Rockies (37-33, second in the NL West)

Pittsburgh Pirates (31-39, fourth in the NL Central) vs. Miami Marlins (25-43, fifth in the NL East)

Arizona Diamondbacks (38-34, third in the NL West) vs. Washington Nationals (32-38, fourth in the NL East)

Seattle Mariners (30-44, fifth in the AL West) vs. Oakland Athletics (36-35, third in the AL West)

Los Angeles Angels (35-36, fourth in the AL West) vs. Tampa Bay Rays (42-28, second in the AL East)